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Ruffalo RR Jr Spradlin TA, Pollock GD, Waddell JE, Murphy PJ. This difference inresults cannot be attributable wholly to theconfounding influence of hearing threshold. Patients with rapid cycling patternmay particularly benefit from valproate therapy.A combination of lithium and valproate maysucceed in cases resistant to monotherapy witheither drug. The 30-day and6-month outcomes between the two strategies wereunchanged (HR: 1.01 [CI: 0.58–1.76], ARR: 0%) andthe reduction in HPR was not significantly predic-tive of outcome (24)

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A patient whodeteriorates from a GCS of 14–10 may be in needof airway protection; while the patient who isimproving from a GCS of 6–8 may not requireinvasive ventilation as long as close, continuousmonitoring is provided. Without thesetwo effector mechanisms possessed by Tregs, rampant autoimmunity and viral/pathogenicinfections would occur in the body

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